Ligand Design for G Protein-coupled Receptors, Volume 30 (Methods and Principles in Medicinal Chemistry)

ISBN 10: 3527312846 / ISBN 13: 9783527312849

Published by Wiley-VCH, 2006

About this Item

A copy that has been read, remains in good condition. All pages are intact, and the cover is intact. The spine and cover show signs of wear. Pages can include notes and highlighting and show signs of wear, and the copy can include "From the library of" labels or previous owner inscriptions. 100% GUARANTEE! Shipped with delivery confirmation, if you're not satisfied with purchase please return item! Ships via media mail.

Seller Inventory # OTV.3527312846.G

Bibliographic Details

• Title: Ligand Design for G Protein-coupled Receptors, Volume 30 (Methods and Principles in Medicinal Chemistry)
• Publisher: Wiley-VCH
• Publication Date: 2006
• Language: English
• ISBN 10: 3527312846
• ISBN 13: 9783527312849
• Binding: Hardcover
• Condition: good

About this title

Synopsis

G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable to a rational drug design.
Based on recent examples from academia and the pharmaceutical industry, this book demonstrates how to apply the whole range of bioinformatics, chemoinformatics and molecular modeling tools to the rational design of novel drugs targeting GPCRs.
Essential reading for medicinal chemists and drug designers working with this largest class of drug targets in the human genome.

About the Author

Didier Rognan leads the Drug Bioinformatics Group at the Laboratory for Molecular Pharmacochemistry in Illkirch (France). He obtained a graduate degree in Pharmacy from the University of Rennes and completed his PhD in Medicinal Chemistry at the University of Strasbourg under the supervision of Camille G. Wermuth in 1989. Moving to the Swiss Federal Institute of Technology in Zürich he became Assistant Professor at the ETH before being named a research director at the CRNS in Illkirch near Strasbourg in 2000.
Professor Rognan is mainly interested in all aspects (method development, applications) of protein-based drug design and virtual screening.