Lipids and Drug Resistance in Fungi: A Study

Language: English

Published by LAP LAMBERT Academic Publishing Mai 2016, 2016

3659855871 / 9783659855870

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This item is printed on demand - Print on Demand Titel. Neuware -Candida albicans is an opportunistic diploid fungus that causes infection in immunocompromised and debilitated patients. Wide spread and prolonged usage of azoles in recent years has led to the rapid development of the phenomenon of azole resistance which poses a major threat to antifungal therapy. Various mechanisms contribute towards the development of resistance in Candida such as overexpression of pumps encoded by genes belonging to ATP-Binding Cassette (ABC) and Major Facilitator Superfamilies of transporters (MFS), and/or mutations in the target enzyme of azoles etc. Based on several studies, a close interaction between membrane lipids and drug extrusion pump proteins has been realized. It has been shown that the action of antifungals is modulated by subtle modification of the membrane lipid composition.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 148 pp. Englisch.

Seller Inventory # 9783659855870

Title
Lipids and Drug Resistance in Fungi: A Study
Author
Ritu Pasrija
Publisher
LAP LAMBERT Academic Publishing Mai 2016
Publication year
2016
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659855871
ISBN 13
9783659855870
Item weight
238 grams
Dimensions
220x150x10 mm

buchversandmimpf2000

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