Lipopolysaccharide Effect on RBC Volume in an In-Vitro Model | Mean Corpuscular Volume Analysis by Micropipette Aspiration Technique before and after Activated Protein C Application | Rabih El Hage | Taschenbuch | Englisch | VDM Verlag Dr. M�ller | EAN 9783639279252 | Verantwortliche Person f�r die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabr�ck, mail[at]preigu[dot]de | Anbieter: preigu.

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Title

Lipopolysaccharide Effect on RBC Volume in an In-Vitro Model | Mean Corpuscular Volume Analysis by Micropipette Aspiration Technique before and after Activated Protein C Application

Publisher

VDM Verlag Dr. M�ller

Publication Date

2010

Language

English

ISBN 10

3639279255

ISBN 13

9783639279252

Binding

Taschenbuch

Condition

Neu

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B�cher

About this title

Synopsis

Recent studies about lipopolysaccharide (LPS) effects were done on red blood cells in in-vivo and in in-vitro models showed that sepsis (or gram negative bacterial sepsis like LPS infection) had effect on red blood cells. Previous studies showed already the immediate anti- aggregant effect of lipopolysaccharide on red blood cells. Remarkably through those experiments, the red blood cells diameter looked as if it increased, judging only by naked eye from saved videos and microscopic images. But there was no specific confirmation that the red blood cells volume did also increase. There comes the need of micropipette aspiration technique, which is itself an accurate single cell technique that carries some very precise tasks, including the determination of red blood cells volume, in our case, the volume change of red blood cells exposed to many chemicals and proteins including lipopolysaccharide and activated protein C (APC).

About the Author

Rabih El Hage, Dipl.-Ing. (FH) Studium der Medizintechnik an der FH Aachen. Verkaufsspezialist bei der Mediline s.a.r.l. - Libanon

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