Long Non-Coding RNAs - Function, Mechanisms, and Applications (Genetics)

ISBN 10: 1836344791 / ISBN 13: 9781836344797

Published by IntechOpen, 2025

About this Item

Seller Inventory # I-9781836344797

Bibliographic Details

• Title: Long Non-Coding RNAs - Function, Mechanisms, and Applications (Genetics)
• Publisher: IntechOpen
• Publication Date: 2025
• Language: English
• ISBN 10: 1836344791
• ISBN 13: 9781836344797
• Binding: Hardcover
• Condition: New

About this title

Synopsis

LncRNAs contribute to cancer progression by regulating gene expression epigenetically and post-transcriptionally. They influence tumorigenesis through interactions with chromatin modifiers, act as competitive endogenous RNAs to modulate microRNA activity and regulate processes such as epithelial-mesenchymal transition (EMT) that facilitate metastasis. LncRNAs affect cancer cell proliferation, apoptosis, migration, metabolism, and drug resistance, making them crucial players in tumor development and potential targets for diagnosis and therapy. The book covers the latest reports about lncRNAs.