The Long and Short Non-coding RNAs in Cancer Biology

Erwei Song

ISBN 10: 9811093679 / ISBN 13: 9789811093678

Published by Springer Nature Singapore Jun 2018, 2018

About this Item

This item is printed on demand - it takes 3-4 days longer - Neuware -The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets. 468 pp. Englisch.

Seller Inventory # 9789811093678

Bibliographic Details

• Title: The Long and Short Non-coding RNAs in Cancer Biology
• Publisher: Springer Nature Singapore Jun 2018
• Publication Date: 2018
• Language: English
• ISBN 10: 9811093679
• ISBN 13: 9789811093678
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 235W x 155H x 26D millimeters 235 millimeters width by 155 millimeters height by 26 millimeters depth
• Weight: 703 grams

About this title

Synopsis

The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.

About the Author

Dr. Erwei Song is a professor at SunYat-Sen Memorial Hospital, Guangzhou, China.