Lymphatic Filariasis: Formulation and evaluation of fixed dose combination - kit for the treatment of lymphatic filariasis

Lymphatic filariasis, considered globally as a neglected tropical disease (NTD), is a parasitic disease caused by microscopic, thread-like worms, the parasite damages the lymph system. Most of the infected people have no symptoms and will never develop clinical symptoms. Fixed dose combination kits have emerged as a potential technique for the treatment of lymphatic filariasis. LF is treated with a mix of pharmacological therapy, vector control, and preventative measures. FDC kits for the treatment of LF are made up of two or more antifilarial medicines that target distinct phases of the parasite's life cycle. These kits make treatment regimens easier to follow, increase patient compliance, and improve overall treatment results. The use of FDC kits in LF therapy has various advantages. It removes the need for patients to take various pills or capsules at different times, decreasing therapy complexity and boosting adherence. Antifilarial medicine combination and dose standardisation decreases the possibility of incorrect drug selection or dosage mistakes. Furthermore, the combination of various medications in FDC kits may aid in the prevention of drug resistance.