Lysosomes

Paul Saftig

ISBN 10: 1441938044 / ISBN 13: 9781441938046

Published by Springer US, Springer US, 2010

About this Item

Druck auf Anfrage Neuware - Printed after ordering - Lysosomes are membrane-surrounded organelles which are present in all animal cells. The importance of this organelle is underlined by an increasing number of human diseases, which are associated with an impaired function of the lysosomal compartment.This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases. In addition to theseclassical topics, new insights into lysosomal functions are covered by chapters dealing with specialized lysosomes involved in bone resorption and plasma membrane repair, the lysosomal transciptome, and proteome and the emerging role of lysosomes in special forms of autophagy.This book will provide readers with a comprehensive overview into how this fascinating organelle works and how research in the field is developing.

Seller Inventory # 9781441938046

Bibliographic Details

• Title: Lysosomes
• Publisher: Springer US, Springer US
• Publication Date: 2010
• Language: English
• ISBN 10: 1441938044
• ISBN 13: 9781441938046
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 229W x 152H x 14D millimeters 229 millimeters width by 152 millimeters height by 14 millimeters depth
• Weight: 352 grams

About this title

Synopsis

Lysosomes are membrane-surrounded organelles which are present in all animal cells. The importance of this organelle is underlined by an increasing number of human diseases, which are associated with an impaired function of the lysosomal compartment.

This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases. In addition to these classical topics, new insights into lysosomal functions are covered by chapters dealing with specialized lysosomes involved in bone resorption and plasma membrane repair, the lysosomal transciptome, and proteome and the emerging role of lysosomes in special forms of autophagy.

This book will provide readers with a comprehensive overview into how this fascinating organelle works and how research in the field is developing.