MATRIX METALLOPROTEINASES IN HEALTH AND DISEASE: Regulators of Tissue Remodeling and Disease Progression

Matrix metalloproteinases (MMPs) have emerged as pivotal enzymes in the regulation of extracellular matrix (ECM) remodeling, orchestrating a wide range of physiological and pathological processes. These zinc-dependent endopeptidases are central to tissue development, wound healing, angiogenesis, and immune responses, while also playing critical roles in pathological conditions such as cancer, cardiovascular disease, arthritis, neurodegeneration, and periodontal disease. As gatekeepers of ECM turnover and modulators of cellular behavior, MMPs have attracted significant attention from researchers and clinicians across the spectrum of biomedical science.Matrix Metalloproteinases in Health and Disease offers a comprehensive, up-to-date exploration of the biology, function, and clinical significance of this powerful enzyme family. This book brings together a multidisciplinary perspective, presenting an integrated view of MMPs from molecular mechanisms to translational applications.