THE MOLECULAR BASIS OF MUTATION

"This book aims to present a broad outline of what is understood about mutational mechanisms and to emphasize many of the doubtful areas . I hope also to stimulate further research into mutational mechanisms themselves, because while the taxonomy of point mutations appears to be well established, it is clear that the experimental evidence supporting many currently popular hypotheses concerning mutational processes is quite inadequate." [Preface, 1969] The chapter headings are: Prospects for a Molecular Description of Mutation; Why Bacteriophages?; Bacteriophage Genetics: First Principles; Genetic Mapping and the Dissection of the Gene; Mutation Rates; Collecting Mutants: Procedures and Precautions; Mutations in Viruses; The Taxonomy of Mutational Lesions; The Origin and Properties of Macrolesions; Transitions; Transversions; Frameshift Mutations; Chemical Mutagenesis; Radiation Mutagenesis; Spontaneous Mutation; Mutational Heterozygotes; Suppression; Complementation and Polarity; and Pseudomutation. 273 (+ xii unnumbered) pages, with Bibliography and 2 Indexes. Boards are slightly sunned; name of prior owner stamped on front endpaper and lower text edge; boards and text otherwise clean and near new.…