Matrix Metalloproteinases in Tissue Remodelling and Inflammation (Progress in Inflammation Research)

Vincent Lagente (Editor), Elisabeth Boichot (Editor)

ISBN 10: 3764385847 / ISBN 13: 9783764385842

Published by Birkhauser, Switzerland, 2008

About this Item

. Pictorial board hardcover, from closed Astra Zeneca company library. Lending record shows this book has never been borrowed, 182 pages, illustrated. Development of selective and non selective inhibitors of MMPs give new insights in the relationship between activation of inflammatory cells and tissue remodelling and advise new therapeutics possibilities to the treatment of inflammatory disease. Contents clean, tight and bright.

Seller Inventory # 029926

Bibliographic Details

• Title: Matrix Metalloproteinases in Tissue Remodelling and Inflammation (Progress in Inflammation Research)
• Publisher: Birkhauser, Switzerland
• Publication Date: 2008
• Language: English
• ISBN 10: 3764385847
• ISBN 13: 9783764385842
• Binding: Hardcover
• Condition: Near Fine
• Book Type: Book
• Seller catalogs:
  • Medical Research

About this title

Synopsis

Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. MMP synthesis and functions are regulated by three major mechanisms including transcriptional activation, post-transcriptional processing, and control of activity by tissue inhibitors of metalloproteinases (TIMPs). Many cell types have been identified as producers of MMPs and TIMPs in a context of inflammatory processes. MMPs are involved in numerous inflammatory diseases, including respiratory, cardiovascular and central nervous system pathologies.

This volume presents new advances in the involvement of MMPs in various diseases associated with inflammatory processes. Moreover, the recent development of selective and non selective inhibitors of MMPs provides new insights in the relationship between activation of inflammatory cells and tissue remodelling and advises new therapeutic possibilities for the treatment of inflammatory diseases.