Mechanisms of Disease A Textbook of Comparative General Pathology

Pathology is a fundamental part of the veterinary curriculum, and all students take at least one semester in general pathology and one in special, or systemic, pathology. Slauson-Cooper has been the book of choice in general veterinary pathology since 1982. It introduces students to disease concepts inherent in clinical medicine through the study of pathogenetic mechanisms and stresses the importance of critical thinking. Pathology is a changing science. Disease is still often caused by various microbes and toxins, but the continuing fascination is with how disease occurs. This classic text focuses on new advances in our understanding of the complex mechanisms by which mammals become sick.

Only text devoted to general veterinary pathology

Good balance between the detail required for sophisticated explanations of disease mechanisms and information overload

Large, clearly reproduced slides accompanied by line drawings that clarify difficult cellular concepts

Clear style of writing makes complex concepts understandable

Outlines, tables, and highlighted essential terms make this text student friendly

Expanded discussion of apoptosis, a process of cell death that is now recognized to be involved in many physiologic and pathologic processes. This process is related to the more conventional view of tissue injury and necrosis.

Updated chapter on inflammation, including discussions on mediators of the immune and inflammatory responses, adhesion molecules involved in the cellular component of the inflammatory response, signalling events in inflammation, and the role of growth factors in tissue repair and wound healing.

Immunopathology completely rewritten to focus the role of immunologic processes in pathologic processes.

New information on the role of genetics in cancer development

New emphasis on genetics in the cause of disease

More than 35 new, clear line drawings illustrating difficult cellular concepts

Several new case studies

Larger book format with a more open, accessible design

David O. Slauson, DVM, PhD, Dipl ACVP, University of Tennessee College of Veterinary Medicine, Knoxville, TN; and Barry J. Cooper, BVSc, PhD, Dipl ACVP, College of Veterinary Medicine, Cornell University, Ithaca, NY