Membrane Defenses Against Attack by Complement and Perforins (Current Topics in Microbiology and Immunology)

Parker, Charles J. (Editor)

ISBN 10: 3642770169 / ISBN 13: 9783642770166

Published by Springer-Verlag, 2012

About this Item

reprint edition. 196 pages. 9.25x6.10x0.50 inches. In Stock.

Seller Inventory # x-3642770169

Bibliographic Details

• Title: Membrane Defenses Against Attack by Complement and Perforins (Current Topics in Microbiology and Immunology)
• Publisher: Springer-Verlag
• Publication Date: 2012
• Language: English
• ISBN 10: 3642770169
• ISBN 13: 9783642770166
• Binding: Paperback
• Condition: Brand New
• Weight: 0.32 kilograms

About this title

Synopsis

In this volume a comprehensive review of membrane proteins that regulate complement and perforin-mediated cytolysis is presented. A detailed analysisis provided of the biochemical, molecular, and functional features of these proteins; the glycosyl phosphatidylinositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CR1 for immune-mediated pathophysiological processes is discussed in a separate section.