Method development for analysis of Amphetamine-type drugs using GC-MS : Forensic Toxicology & drugs Abuse

Language: English

Published by LAP LAMBERT Academic Publishing, 2013

365945267X / 9783659452673

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nach der Bestellung gedruckt Neuware - Printed after ordering - Forensic toxicology is the application of toxicology to the matter of law. This work is based on forensic drug testing field of forensic toxicology. Nowadays, the abusing of drugs is considered as a very intense problem which occurring in communities. More and more people are getting addicted to drugs and many are the drug dealers. The main purpose of the present study was the drug profiling and identification of eight Amphetamine-type stimulants (d-amphetamine sulphate, (+)-methamphetamine, Ibuprofen, Piperazine hexahydrate, 1-(4-methoxyphenyl) piperazine, 1-(4-trifluoromethylphenyl) piperazine, 1-Benzylpiperazine and 1-(2-methoxyphenyl) piperazine) by developing a GC-MS method which would detect all the above drugs at the same time. Quinoline was used as internal standard (IS) during the present GC-MS analysis. The first step was the individual drug analysis by the developed GC-MS method and the next step was the mixed drug analysis. The drugs were derivatised by the acylation reagent PFPA, however the silylation reagent BSTFA:TMCS (99:1) was also used as an alternative to acylation. The standard curve of each drug was plotted and the LOD & LOQ was calculated.

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Title
Method development for analysis of Amphetamine-type drugs using GC-MS : Forensic Toxicology & drugs Abuse
Author
Mahesh Sharma
Publisher
LAP LAMBERT Academic Publishing
Publication year
2013
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
365945267X
ISBN 13
9783659452673
Item weight
179 grams
Dimensions
220x150x7 mm

AHA-BUCH GmbH

Einbeck, Germany

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