Methods in Bioengineering: Organ Preservation and Reengineering (The Artech House Methods in Bioengineering Series)

Written and edited by recognized experts in the field, the new Artech House Methods in Bioengineering book series offers detailed guidance on authoritative methods for addressing specific bioengineering challenges. Offering a highly practical presentation of each topic, each book provides research engineers, scientists, and students with step-by-step procedures, clear examples, and effective ways to overcome problems that may be encountered. This first-of-its-kind volume addresses the important challenge of organ preservation and reengineering. The book presents cutting-edge techniques for damaged livers and hearts via normothermic perfusion, hypothermic machine perfusion for the liver, kidney and pancreas, and imaging techniques to assess the viability of injured kidneys. Professionals and researchers also find methods to decellularize whole organs to create scaffolds for tissue engineering. Moreover, the book presents an approach to enhancing hepatocyte recovery from marginal livers.

Korkut Uygun is the leader of the Organ Engineering Group at Massachusetts General Hospital, where he was instrumental in developing a technique that promises to allow growth of transplantable replacement livers. Dr. Uygun received his Ph.D. in chemical engineering from Wayne State University. Charles Y. Lee is an associate professor in the Department of Medical Engineering at the University of North Carolina, Charlotte. Dr. Lee earned his Ph.D. in mechanical engineering from the University of California, Berkeley.