Volume 493. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1300grams, ISBN:9780123812742.

Seller Inventory # 5410207

Contact seller

Report this item

Bibliographic Details

Title

Methods In Enzymology: Fragment Based Drug Design: Tools, Practical Approaches, and Examples (Volume 493)

Publisher

Academic Press

Publication Date

2011

Language

English

ISBN 10

0123812747

ISBN 13

9780123812742

Binding

Hardcover

Condition

Good

Weight

1300 grams

Seller catalogs

Science & Technology

About this title

Synopsis

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits.

Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens
The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD

"About this title" may belong to another edition of this title.

Store Description

Based in central Lincoln, Anybook Ltd. sells exclusively on line. We specialise in academic works. All our books are in good condition or better, unless otherwise described. We will respond to your enquiry promptly and mail books out within 24 hours of receiving payment. We use Royal Mail and other reputable couriers at greatly discounted postage rates. If you find cheaper postage from the UK, we'll match it. Remember if you are unsatisfied in any way with any purchase, we will give you a complete and unconditional refund. All books are hand wrapped. All e-mails answered personally. All books are offered subject to being unsold.

Visit Seller's Storefront

Seller's business information

Anybook Ltd.
28 West End,, Burgh le Marsh,, Lincolnshire, PE24 5EY, United Kingdom

Sale & Shipping Terms

Terms of Sale

Anybook Ltd is a company registered in England and Wales. Company Registration Number: 3692291. VAT Number: GB753406145. Share Capital GBP100.

Registered Offices:
28 West End,
Burgh le Marsh,
Lincolnshire,
PE24 5EY
UK

Customer Services:
2,Outer Circle Business Park,
Outer Circle Road,
Lincoln
LN2 4HX
UK

Email Address: sales@anybook.com
Telephone Number: +44 (0) 115 888 2269
Authorized Representative: Ms. Claire Williams

Shipping Terms

Orders usually ship within 1 business day. We use Royal Mail and other reputable couriers at greatly discounted postage rates. If your book order is heavy or over-sized, or valuable enough to require tracking, we may contact you to let you know extra shipping is required.

Shipping rates from United Kingdom to U.S.A.

Shipping rates from United Kingdom to U.S.A.
Order quantity	5 to 10 business days	1 to 3 business days
First item	US$ 18.27	US$ 37.42

Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.