Methods in Enzymology Volume 231 Hemoglobin Part B Biochemical and Analytical Methods

Everse, Johannes; Vandergriff, Kim D. and Winslow, Robert M.

ISBN 10: 0121821323 / ISBN 13: 9780121821326

Published by Academic Press, Inc., New York, 1994

About this Item

Covers have minor wear and soil. Corners and ends of spine lightly bumped. Binding tight. No writing. xxx + 743 pages including indexes. Biochemical and analytic focus on the study of human and animal hemoglobin. Black and white figures. Size: 6 x 9.25.

Seller Inventory # 042175

Bibliographic Details

• Title: Methods in Enzymology Volume 231 Hemoglobin Part B Biochemical and Analytical Methods
• Publisher: Academic Press, Inc., New York
• Publication Date: 1994
• Language: English
• ISBN 10: 0121821323
• ISBN 13: 9780121821326
• Binding: Hardcover
• Condition: Good
• Seller catalogs:
  • Science/Technology/Construction

About this title

Synopsis

Hemoglobin has been involved in the most significant advances in our understanding of modern genetics and molecular biology. Now, hemoblobin is again central to a new area: development of artificial blood (blood substitute.) This volume of Methods in Enzymology and its companion, Volume 232, will be indispensable to anyone with a serious interest in this emerging field. They completely update and extend the information presented in Volume 76 published a decade ago.

• Preparation, purification, and analysis of human hemoglobin and of various non-human hemoglobins
• Preparation of hemoglobin hybrids and of model heme compounds
• Preparation of chemically modified hemoglobins and of recombinant hemoglobins
• Analytical procedures presented for studying hemoglobin stability and degradation and for the formation of xenobiotic adducts of hemoglobin

About the Author

Professor Winslow received his M.D. degree and postgraduate training in internal medicine and hematology at the Johns Hopkins University and Hospital. He studied hemoglobin biochemistry at the Massachusetts Institute of Technology and Molecular Biology at the National Institutes of Health. His research, for more than 30 years, has been aimed at the intersection of the synthesis, structure and function of hemoglobin, in such areas as sickle cell anemia, high altitude physiology and hemoglobin-based oxygen carriers. Professor Winslow previously headed the Blood Research Division at the Letterman Army Institute of Research, responsible for the US Army's blood substitute program. Between 1991 and 1998, he was a Professor of Medicine, leading a blood substitute program at the University of California at San Diego (UCSD), supported by the National Institutes of Health. Professor Winslow has also served as a consultant to many private companies and has been an advisor for, among others, the Federal Aviation Administration (FAA), Food and Drug Administration (FDA), the Institute of Medicine of the National Academy of Science, the Pan American Health Organization, the National Institutes of Health, the Department of Defense and a number of foreign governments. He has written more than 200 scientific articles on clinical, physiological and biochemical aspects of hemoglobin and oxygen transport.