Methods in Enzymology (Volume 256): Small GTPases and Their Regulators, Part B - Rho Family

General Description of the Volume:
Small GTPases play a key role in many aspects of contemporary cell biology: control of cell growth and differentiation; regulation of cell adhesion and cell movement; the organization of the actin cytoskeleton; and the regulation of intracellular vesicular transport. This volume plus its companion Volumes 255 and 257 cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level. It is the first compendium of practical techniques for working with small GTPases of the Rho group.
General Description of the Series:
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Praise for the Volume
"This book makes a unique contribution...it is...the first place to turn when thinking about how to measure, analyze, and interpret the thermodynamics of conformational change and interactions of proteins and nucleic acids. It would make a fine textbook for a graduate course...Instructors who teach courses in less depth will find it an important background reference. For researchers, it belongs not just in the library, but on the personal bookshelf of anyone who is serious about research in molecular biophysics.."
--Victor A. Bloomfield, University of Minnesota, in BIOPHYSICAL JOURNAL
"These books are a most useful and valuable resource to everyone involved in the field of protein research. They will certainly serve as guidance books and many of the techniques described might remain central to the field of signal transduction in the future."
--Tilat A. Rizvi, University of Cincinnati Medical Center, in TINS
Praise for the Series
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
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"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
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--JOURNAL OF CHROMATOGRAPHY