MicroRNAs: From Basic Science to Disease Biology

Krishnarao Appasani

ISBN 10: 0521865980 / ISBN 13: 9780521865982

Published by Cambridge University Press, 2008

Verschmutzung / Wasserschaden; Abnutzung / Risse - leicht; Gebrochener Buchrücken / Seiten oder Softcover umgeknickt. MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their recent discovery is revolutionising both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development.Forewords Sidney Altman, Yale University, Winner of the Nobel Prize in Chemistry, 1989andVictor R. Ambros, Dartmouth Medical School, Co-discoverer of MicroRNAs. Seller Inventory # 1d7a642f-6049-40c7-b7bd-df07b1b257be

Synopsis:

MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their recent discovery is revolutionising both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development.

Forewords by:
Sidney Altman, Yale University, Winner of the Nobel Prize in Chemistry, 1989
and
Victor R. Ambros, Dartmouth Medical School, Co-discoverer of MicroRNAs

Book Description: This wide-ranging reference work will be an invaluable resource for all those wishing to use miRNA techniques in their own research, both in academia and industry. From their discovery, functions and detection to their role in disease biology, this volume uniquely integrates basic miRNA biology with future applications.

Bibliographic Details

Title: MicroRNAs: From Basic Science to Disease ...
Publisher: Cambridge University Press
Publication Date: 2008
Binding: Hardcover
Condition: Fair