Microbial DNA and Host Immunity

Eyal Raz

ISBN 10: 1468497286 / ISBN 13: 9781468497281

Published by Humana Press Okt 2012, 2012

About this Item

This item is printed on demand - it takes 3-4 days longer - Neuware -Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS , the process of cell activation, and the potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis). 428 pp. Englisch.

Seller Inventory # 9781468497281

Bibliographic Details

• Title: Microbial DNA and Host Immunity
• Publisher: Humana Press Okt 2012
• Publication Date: 2012
• Language: English
• ISBN 10: 1468497286
• ISBN 13: 9781468497281
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 235W x 155H x 24D millimeters 235 millimeters width by 155 millimeters height by 24 millimeters depth
• Weight: 645 grams

About this title

Synopsis

Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS , the process of cell activation, and the potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis).

From the Back Cover

The immunostimulatory prospects of bacterial DNA have attracted the interest and attention of scientists and physicians and become a major focus in immunobiology and biomedicine. These activities are the product of immunostimulatory DNA sequences (ISS, also known as GpG motifs), which are rare in the mammalian genome. ISS were shown to enhance immunological responses and were used to confer protection to a wide variety of tumors, allergic inflammation, and infections. In Microbial DNA and Host Immunity, leading researchers review the activation of the mammalian immune system by bacterial DNA and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS, the process of cell activation, and potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis).
Up-to-date and informative, Microbial DNA and Host Immunity illuminates the immunobiology of bacterial DNA and its promise of powerful new vaccines to provide protective immunity against infections, tumors, and chronic disease.