Modeling of Kinases Inhibitors : 3D-QSAR, Moecular Docking and ADMET

Language: English

Published by Noor Publishing Sep 2020, 2020

6202789360 / 9786202789363

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Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

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This item is printed on demand - Print on Demand Titel. Neuware -The human kinome contains 518 proteins. They share a common mechanism of protein phosphorylation known to play an important role in cellular signaling pathways. Impaired kinase function is recognized to be involved in severe diseases like cancer. The challenge of this PhD work is the in silico identification of potentially interesting molecules concerning the inhibitory process of a set of protein kinases, namely PIM1, PIM2, CDC7, DRAK2 and CAMKII¿. The faculty of this protein to interact in differentiation, proliferation and tissue repair phenomena makes their inhibitions crucial for treatments against tumor development in which they are involved. Despites their interests, until now there is no molecule acting on theses kinases has been proven by the Food and Drug Administration. In this way, the authors will focus, in this book on several in silico methods for rational drug design of new kinases inhibitors.Books on Demand GmbH, Überseering 33, 22297 Hamburg 144 pp. Englisch.…

Seller Inventory # 9786202789363

Title
Modeling of Kinases Inhibitors : 3D-QSAR, Moecular Docking and ADMET
Author
Adnane Aouidate
Publisher
Noor Publishing Sep 2020
Publication year
2020
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6202789360
ISBN 13
9786202789363
Item weight
233 grams
Dimensions
220x150x10 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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AbeBooks seller since January 23, 2017

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