Molecular Biophysics of the Extracellular Matrix
Arnott, Struther; Rees, D. A.; Morris, E. Ronald
ISBN 10: 1461295939 ISBN 13: 9781461295938
Published by Humana Press Inc., 2011
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Num Pages: 189 pages, biography. BIC Classification: PSF. Category: (G) General (US: Trade). Dimension: 229 x 152 x 11. Weight in Grams: 306. . 2011. Softcover reprint of the original 1st ed. 1984. Paperback. . . . . Seller Inventory # V9781461295938
Synopsis:
Biopolymers, such as proteins and nucleic acids have been subjected to a rational succession of structural studies in which the determination of chemical compositions, link- ages, and sequences is followed by investigations of molecu- lar architecture and interactions. By the end of the 1960s the covalent structures of glycosaminoglycans and proteo- glycans had been defined both within the carbohydrate chains and in respect to their linkages to protein. The scene was therefore set for successful probing of three- dimensional shapes and intermolecular associations. For- tunately, during the 1970s appropriate physical methods were themselves greatly increasing in power. Consequently much progress has been made using X-ray diffraction anal- ysis of hydrated films, nuclear magnetic resonance spectro- scopy, and chromatographie methods for investigation of molecular interactions in solution. We now have a great deal of information about molecular shapes, their sensitiv- ity to environment (especially associated cations), and their modes of interaction that could be relevant to super- molecular assemblies in biological milieux. For these rea- sons we judged that it would be timely to distil the main conclusions from this phase of research to prepare for the next, which will involve detailed study of the interplay be- tween biological function and molecular structure. The idea for this volume emerged from a workshop meeting at Colworth sponsored by the Biochemical Society.
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Title: Molecular Biophysics of the Extracellular ...
Publisher: Humana Press Inc.
Publication Date: 2011
Binding: Soft cover
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Molecular Biophysics of the Extracellular Matrix
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Biopolymers, such as proteins and nucleic acids have been subjected to a rational succession of structural studies in which the determination of chemical compositions, link ages, and sequences is followed by investigations of molecu lar architecture and interactions. By the end of the 1960s the covalent structures of glycosaminoglycans and proteo glycans had been defined both within the carbohydrate chains and in respect to their linkages to protein. The scene was therefore set for successful probing of three dimensional shapes and intermolecular associations. For tunately, during the 1970s appropriate physical methods were themselves greatly increasing in power. Consequently much progress has been made using X-ray diffraction anal ysis of hydrated films, nuclear magnetic resonance spectro scopy, and chromatographie methods for investigation of molecular interactions in solution. We now have a great deal of information about molecular shapes, their sensitiv ity to environment (especially associated cations), and their modes of interaction that could be relevant to super molecular assemblies in biological milieux. For these rea sons we judged that it would be timely to distil the main conclusions from this phase of research to prepare for the next, which will involve detailed study of the interplay be tween biological function and molecular structure. The idea for this volume emerged from a workshop meeting at Colworth sponsored by the Biochemical Society.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 204 pp. Englisch. Seller Inventory # 9781461295938
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Molecular Biophysics of the Extracellular Matrix
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Molecular Biophysics of the Extracellular Matrix
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