Molecular Diagnostics of Cancer

Siegfried Neumann

ISBN 10: 3540554769 / ISBN 13: 9783540554769

Published by Springer Berlin Heidelberg, Springer Berlin Heidelberg, 1992

About this Item

Druck auf Anfrage Neuware - Printed after ordering - Present and potential future applications of new diagnosticstrategies basedon the direct or indirect detection ofcancer genes are delineated in this volume. Among themethodological aspects covered are enzymatic targetamplification by the polymerase chain reaction and relatedtechniques, DNA fingerprinting, transfer of putative cancergenes in appropriate receipient cells, and recentdevelopments inthe application of monoclonal antibodies inimmunohistochemistry and immunoscintigraphy. The diagnosticand functional implications of mutations in cancer genessuch as ras and p53 are described. The characterization ofcancer genes and their products is correlated with growthcontrol anddissemination of tumour cells by in vitro orclinical evidence. The contributions in the present volumeuptdate the information available on established or newlydescribed cancer genes, and may help manage the transitionfrom basic research to clinical practice.

Seller Inventory # 9783540554769

Bibliographic Details

• Title: Molecular Diagnostics of Cancer
• Publisher: Springer Berlin Heidelberg, Springer Berlin Heidelberg
• Publication Date: 1992
• Language: English
• ISBN 10: 3540554769
• ISBN 13: 9783540554769
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 235W x 155H x 13D millimeters 235 millimeters width by 155 millimeters height by 13 millimeters depth
• Weight: 365 grams

About this title

Synopsis

Present and potential future applications of new diagnostic strategies basedon the direct or indirect detection of cancer genes are delineated in this volume. Among the methodological aspects covered are enzymatic target amplification by the polymerase chain reaction and related techniques, DNA fingerprinting, transfer of putative cancer genes in appropriate receipient cells, and recent developments inthe application of monoclonal antibodies in immunohistochemistry and immunoscintigraphy. The diagnostic and functional implications of mutations in cancer genes such as ras and p53 are described. The characterization of cancer genes and their products is correlated with growth control anddissemination of tumour cells by in vitro or clinical evidence. The contributions in the present volume uptdate the information available on established or newly described cancer genes, and may help manage the transition from basic research to clinical practice.