Molecular Modeling: Basic Principles and Applications

Hans-Dieter HÃ ltje, Wolfgang Sippl, Didier Rognan, Gerd Folkers

ISBN 10: 3527315683 / ISBN 13: 9783527315680

Published by Wiley-VCH February 2008, 2008

About this Item

used trade paperback edition. lightly shelfworn, corners slightly bumped. pages and binding are clean, straight and tight. there are no marks to the text or other serious flaws.

Seller Inventory # 1243150

Bibliographic Details

• Title: Molecular Modeling: Basic Principles and Applications
• Publisher: Wiley-VCH February 2008
• Publication Date: 2008
• Language: English
• ISBN 10: 3527315683
• ISBN 13: 9783527315680
• Binding: Trade Paperback
• Edition: 3rd Edition
• Condition: VG-
• Seller catalogs:
  • SCI chemistry

About this title

Synopsis

Ideal for beginners, this book explains the basics of modeling in a competent yet easily understandable way. Following complete sections on the modeling of small molecules, protein modeling and chemogenomics, completely worked-out examples show the way to the reader's first modeling experiment.
This new, third edition features a new chapter on chemogenomics, reflecting the trend towards 'chemical biology', as well as the protein modeling example being completely rewritten for a better 'feel' of modeling complex biomolecules.
The authors are experienced university teachers who regularly hold courses on molecular modeling, making this a tried-and-tested text for teachers. It is equally valuable for experts, since it is the only book to evaluate the strengths and limitations of the molecular modeling techniques and software currently available.

About the Author

Hans-Dieter Holtje is director of the Institute of Pharmaceutical Chemistry at the Heinrich-Heine-Universitat Dusseldorf (Germany) where he also holds the chair of Medicinal Chemistry. His main interest is the molecular mechanism of drug action.

Wolfgang Sippl is Professor of Pharmaceutical Chemistry at the Martin-Luther-University of Halle-Wittenberg (Germany). He is interested in 3D QSAR, molecular docking and molecular dynamics, and their applications in drug design and pharmacokinetics.

Didier Rognan leads the Drug Bioinformatics Group at the Laboratory for Molecular Pharmacochemistry in Illkirch (France). He is mainly interested in all aspects (method development, applications) of protein-based drug design and virtual screening.

Gerd Folkers is Professor of Pharmaceutical Chemistry at the ETH Zurich (Switzerland). The focus of his research is the molecular interation between drugs and their binding sites.