Multicomponent One Pot Green Synthesis of 1, 5-Benzodiazepines

Language: English

Published by LAP LAMBERT Academic Publishing Dez 2012, 2012

3845422580 / 9783845422589

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This item is printed on demand - Print on Demand Titel. Neuware -Multicomponent Reactions (MCRs) are a promising and vital field of green chemistry. Benzodiazepines are widely used class of bioactive compounds due to their remarkable biological and pharmacological properties. However, many of the methods of synthesis of benzodiazepines suffer major or minor limitations like tedious work up procedure, applications of expensive and hazardous catalyst, long reaction times, unsatisfactory yields, require separation of the catalyst from the product and formation of side products. In our project, we have reviewed the various heterogenous and homogenous catalysts utilized for the synthesis of 1, 5-benzodizepines in the last decade and explored the novel, non-expensive, easily available, non toxic catalyst for the efficient synthesis of 1,5-benzodiazepines under solvent-free conditions. The catalytic efficiency of various acids studied, are categorized in four categories with their proposed mechanism of actions: Amino acids, Aliphatic acids, Aromatic acids and Miscellaneous acids. The remarkable features of these new acid catalysts are high yield, short reaction times, cleaner reaction profiles and high regioselectivity.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 136 pp. Englisch.…

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Title
Multicomponent One Pot Green Synthesis of 1, 5-Benzodiazepines
Author
Akshdeep Sandhar
Publisher
LAP LAMBERT Academic Publishing Dez 2012
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3845422580
ISBN 13
9783845422589
Item weight
221 grams
Dimensions
220x150x9 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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