Multiparticulate Drug Delivery : Formulation, Processing and Manufacturing

Ali R. Rajabi-Siahboomi

ISBN 10: 1493983679 / ISBN 13: 9781493983674

Published by Springer, Springer US, 2018

About this Item

Druck auf Anfrage Neuware - Printed after ordering - Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.

Seller Inventory # 9781493983674

Bibliographic Details

• Title: Multiparticulate Drug Delivery : Formulation, Processing and Manufacturing
• Publisher: Springer, Springer US
• Publication Date: 2018
• Language: English
• ISBN 10: 1493983679
• ISBN 13: 9781493983674
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 235W x 155H x 23D millimeters 235 millimeters width by 155 millimeters height by 23 millimeters depth
• Weight: 616 grams

About this title

Synopsis

Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.

About the Author

Ali Rajabi-Siahboomi is Vice President and Chief Scientific Officer at Colorcon Inc. He obtained his PhD in Pharmacy from University of Nottingham (UK). Dr. Rajabi-Siahboomi held various academic positions in Nottingham and Liverpool JM Universities (UK), before joining Colorcon. His main research interests are in the area of solid dosage form pharmaceutics and pharmaceutical technology with emphasis on oral drug delivery systems. He has published over 150 articles, book chapters, abstracts and patents.