Multiple Drug Resistance in Cancer | Cellular, Molecular and Clinical Approaches

Martin Clynes

ISBN 10: 9401043558 / ISBN 13: 9789401043557

Published by Springer, 2012

About this Item

Multiple Drug Resistance in Cancer | Cellular, Molecular and Clinical Approaches | Martin Clynes | Taschenbuch | viii | Englisch | 2012 | Springer | EAN 9789401043557 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Seller Inventory # 105988061

Bibliographic Details

• Title: Multiple Drug Resistance in Cancer | Cellular, Molecular and Clinical Approaches
• Publisher: Springer
• Publication Date: 2012
• Language: English
• ISBN 10: 9401043558
• ISBN 13: 9789401043557
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 260W x 195H x 22D millimeters 260 millimeters width by 195 millimeters height by 22 millimeters depth
• Weight: 849 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

This book is an up-to-date review of current knowledge in the field of multiple drug resistance in human cancer. The literature up to the middle of 1993 is surveyed in specialist chapters written by different experts. Topics covered include the molecular genetics, cytogenetics and biochemistry of the mdr genes and P-glycoprotein; alternative transport proteins in MDR; topoisomerases I and II; cytochrome p450-enzymes and glutathione- S-transferases in MDR; cellular models for MDR in solid tumours and haemopoietic tumours; immunochemical and molecular biological techniques for detection of MDR-related gene expression; and clinical and pharmacological strategies to circumvent resistance. The book brings together a new combination of approaches to this serious clinical problem.

About the Author

Clynes, Dublin, Ireland