Mutation Randomness And Evolution

The author draws on a detailed knowledge of mutational mechanisms to argue that the randomness doctrine is best understood, not as a fact-based conclusion, but as the premise of a neo-Darwinian research program focused on selection.

Arlin Stoltzfus, Fellow, Institute for Bioscience and Biotechnology Research, Rockville, Maryland, USA

Arlin Stoltzfus is a Fellow of the Institute for Bioscience and Biotechnology Research, and a Research Biologist at the National Institute of Standards and Technology in Gaithersburg, Maryland, USA . He is an evolutionary biologist who uses computer-based approaches to study evolution at the molecular level. His primary interest has been to develop and evaluate theories about evolutionary factors other than natural selection. He and his coworkers proposed the theory of Constructive Neutral Evolution, and showed theoretically that biases in the introduction of variation may impose biases on evolution without requiring neutrality.