Myelin Basic Protein

Frederic P. Miller

ISBN 10: 6131857237 / ISBN 13: 9786131857232

Published by Omniscriptum Mär 2026, 2026

About this Item

This item is printed on demand - Print on Demand Titel. Neuware -Please note that the content of this book primarily consists of articlesavailable from Wikipedia or other free sources online. Myelin basicprotein (MBP) is a protein believed to be important in the process ofmyelination of nerves in the central nervous system (CNS). MBP wasinitially sequenced in 1979 after isolation from myelin membranes a.Since that time, knockout mice deficient in MBP have been developedwhich showed decreased amounts of CNS myelination and a progressivedisorder characterized by tremors, seizures, and early death. The genefor MBP is on chromosome 18; the protein localizes to the CNS and tovarious cells of the hematopoietic system. The pool of MBP in thecentral nervous system is very diverse, with several splice variantsbeing expressed and a large number of post-translational modificationson the protein, which include phosphorylation, methylation, deamidationand citrullination. In melanocytic cell types MBP gene expression may beregulated by MITF a.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 120 pp. Englisch.

Seller Inventory # 9786131857232

Bibliographic Details

• Title: Myelin Basic Protein
• Publisher: Omniscriptum Mär 2026
• Publication Date: 2026
• Language: English
• ISBN 10: 6131857237
• ISBN 13: 9786131857232
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 8D millimeters 220 millimeters width by 150 millimeters height by 8 millimeters depth
• Weight: 197 grams

About this title

Synopsis

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the central nervous system (CNS). MBP was initially sequenced in 1979 after isolation from myelin membranes a. Since that time, knockout mice deficient in MBP have been developed which showed decreased amounts of CNS myelination and a progressive disorder characterized by tremors, seizures, and early death. The gene for MBP is on chromosome 18; the protein localizes to the CNS and to various cells of the hematopoietic system. The pool of MBP in the central nervous system is very diverse, with several splice variants being expressed and a large number of post-translational modifications on the protein, which include phosphorylation, methylation, deamidation and citrullination. In melanocytic cell types MBP gene expression may be regulated by MITF a.