Myotonic Dystrophy

This book provides a full and practical account of management of myotonic dystrophy, the commonest muscular dystrophy of adult life and a condition of exceptional variability. Written for neurologists, clinical geneticists and other clinical geneticists and other clinical specialties involved with the disorder, it deals with both the neurological aspects and also the wide range of systematic complications that may occur. In addition it provides details of information and support available to patients and families and gives a summary of the present state of clinical trials of therapeutic agents. These sections are preceded by general introductory chapters describing both the clinical features and also the current state of research into understanding the underlying mechanisms.

Peter Harper is a Professor and Consultant in Medical Genetics, Institute of Medical Genetics, University of Wales College of Medicine, Cardiff. Baziel van Engelen is in the Department of Neurology, University of Nijmegen, The Netherlands. Bruno Eymard is at La Salpetriere Hospital, Paris. Douglas Wilcox is at University of Glasgow.