NMR:Study of charge transfer complexation and proteins: Study of charge transfer complexation with DDQ and Delineating the determinants of backbone motions of small proteins

Khan, Nadeem, D, Krishna

ISBN 10: 3845408448 / ISBN 13: 9783845408446

Published by LAP LAMBERT Academic Publishing, 2011

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Bibliographic Details

• Title: NMR:Study of charge transfer complexation and proteins: Study of charge transfer complexation with DDQ and Delineating the determinants of backbone motions of small proteins
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2011
• Language: English
• ISBN 10: 3845408448
• ISBN 13: 9783845408446
• Binding: Paperback
• Condition: Like New
• Book Type: book

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Synopsis

Charge transfer complexation between Rabeprazole and 2,3-dichloro-5,6-dicyano -1,4-benzoquinone (DDQ) as an acceptor has been investigated spectrophotometrically. Based on Job’s method of continuous variation plots, the obtained results indicate the formation of 1:1 Charge transfer complex with general formula [(RA) (DDQ)] and Analyses carried out using literature data for backbone 15N NMR relaxation of 20 proteins that differ widely in their sequence, structure, and function show that the segments with defined secondary structural elements are generally stiff relative to less structured or unstructured regions.

About the Author

I am a Ph.D in Analysis of Drugs in Pharmaceutical formulations and Biological samples Aligarh Muslim University, Aligarh, India in the year 2003 and spent 2 years as Postdoctoral fellow in Taiwan working in the field Mass spectrometry. Currently working as a Scientist in Jubilant Lifescience pvt Ltd, India and taking care of Analytical dvivision.