Nano-Aggregate Of Block Copolymers In Aqueous Solutions: Incorporation And Release Of Anionic Drugs In Polymeric Micelles

Khanal, Anil; Khanal, Anil

ISBN 10: 3845407395 / ISBN 13: 9783845407395

Published by Lap Lambert Academic Publishing, 2011

About this Item

112 pages. 8.66x5.91x0.26 inches. In Stock.

Seller Inventory # __3845407395

Bibliographic Details

• Title: Nano-Aggregate Of Block Copolymers In Aqueous Solutions: Incorporation And Release Of Anionic Drugs In Polymeric Micelles
• Publisher: Lap Lambert Academic Publishing
• Publication Date: 2011
• Language: English
• ISBN 10: 3845407395
• ISBN 13: 9783845407395
• Binding: Paperback
• Condition: Brand New
• Weight: 0.21 kilograms

About this title

Synopsis

When ionic anticancer drugs are used without drug delivery systems, they are absorbed in the entire body. This decreases the effectiveness of the drugs. In order to circumvent these demerits, micelles of AB and ABA diblock copolymer are used for the delivery of ionic drugs. But, most of these micelles get collapsed in the blood stream. Hence, these micelles are not effective for the delivery of ionic drugs. Hence, this book describes extensive research works on the frozen micelles based on the ABC triblock copolymers. This frozen micelle does not collapse immediately even it is diluted extremely in the blood stream. Hence, this micelle serves as a long-circulating drug carrier. This book also describes physicochemical properties of frozen micelles with drugs, polymers, surfactants, dyes and also describes mathematical modeling to predict the release kinetics of drugs from the micelle. It also describes the fabrication of nano-hybrids complexes because these complexes may give a new approach to nanotechnology. This book is useful for anyone who is interested in the formulation of drug, food, nanotechnology, polymer, colloid and surface chemistry.

About the Author

Anil Khanal, Ph.D. in Chemistry from Saga University, Japan. Postdoctoral Fellow at University of Western Ontario, Canada