Natural Killer T-Cells : Roles, Interactions, & Interventions

Language: English

Published by Nova Science Publishers Inc Jul 2008, 2008

1604562870 / 9781604562873

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Neuware - Natural killer T (NKT) cells are a heterogeneous group of T cells that share properties of both T cells and natural killer (NK) cells. Many of these cells recognize the non-polymorphic CD1d molecule, an antigen-presenting molecule that binds self- and foreign lipids and glycolipids. Upon activation, NK T cells are able to produce large quantities of interferon-gamma, IL-4, and granulocyte-macrophage colony-stimulating factor, as well as multiple other cytokines and chemokines (such as IL-2 and TNF-alpha). NKT cells seem to be essential for several aspects of immunity because their dysfunction or deficiency has been shown to lead to the development of autoimmune diseases (such as diabetes or atherosclerosis) and cancers. NKT cells have recently been implicated in the disease progression of human asthma. The clinical potential of NKT cells lies in the rapid release of cytokines (such as IL-2, IFN-gamma, TNF-alpha, and IL-4) that promote or suppress different immune responses.

Seller Inventory # 9781604562873

Title
Natural Killer T-Cells : Roles, Interactions, & Interventions
Author
Nathan V Fournier
Publisher
Nova Science Publishers Inc Jul 2008
Publication year
2008
Condition
Neu
Binding
Buch
Language
English
ISBN 10
1604562870
ISBN 13
9781604562873
Item weight
680 grams
Dimensions
264x186x18 mm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

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