A New Algorithm for the Management of Dermatofibrosarcoma Protuberans | A Thesis Submitted to the Yale University School of Medicine in Partial Fulfillment of the Requirements for the Degree of Doctor of Medicine

Carolyn Goldberg (u. a.)

ISBN 10: 3843392366 / ISBN 13: 9783843392365

Published by LAP LAMBERT Academic Publishing, 2011

About this Item

A New Algorithm for the Management of Dermatofibrosarcoma Protuberans | A Thesis Submitted to the Yale University School of Medicine in Partial Fulfillment of the Requirements for the Degree of Doctor of Medicine | Carolyn Goldberg (u. a.) | Taschenbuch | 52 S. | Englisch | 2011 | LAP LAMBERT Academic Publishing | EAN 9783843392365 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Seller Inventory # 107119067

Bibliographic Details

• Title: A New Algorithm for the Management of Dermatofibrosarcoma Protuberans | A Thesis Submitted to the Yale University School of Medicine in Partial Fulfillment of the Requirements for the Degree of Doctor of Medicine
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2011
• Language: English
• ISBN 10: 3843392366
• ISBN 13: 9783843392365
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 4D millimeters 220 millimeters width by 150 millimeters height by 4 millimeters depth
• Weight: 96 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

The purpose of this project was to design an algorithm for the management of Dermatofibrosarcom Protuberans (DFSP.) The National Cancer Center Network guidelines suggest immediate reconstruction in most cases after DFSP resection. We believe this algorithm is inadequate. Due to the infiltrating nature of DFSP, tumor margins are often positive after resection. Immediate reconstruction in the context of residual tumor is problematic because of the risk for spreading microscopic disease and the potential to compromise reconstructive options. Here we examined the prevalence of positive margins on permanent pathology after immediate closure following surgical resection of DFSP. Forty percent of patients who underwent immediate closure were found to have positive margins on permanent pathology. Given these findings, we propose a treatment algorithm focused on more conservative surgical management of DFSP in which negative margins are established before closure. Mohs surgery, which allows for immediate identification of pathology, plays a central role.

About the Author

Carolyn Goldberg graduated from Brown University in 2005 and from Yale School of Medicine in 2010. She is currently a resident in Plastic and Reconstructive Surgery at the University of Wisconsin.