New method development and validation of sensitive LC-MS/MS method : for Quantification of nitrosoamine impurities in Glimepride active ingredient

Language: English

Published by LAP LAMBERT Academic Publishing, 2026

663025810X / 9786630258103

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - The analysis of nitrosoamine impurities using liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a critical process in pharmaceutical and food safety testing. Nitrosoamines are known for their potential carcinogenic properties, making their detection and quantification essential. LC-MS/MS offers high sensitivity and specificity, allowing for the effective separation and identification of these compounds in complex matrices. The methodology typically involves sample preparation, which may include extraction and purification steps to isolate nitrosoamines from the sample matrix. Following this, the samples are subjected to LC-MS/MS, where the liquid chromatography component separates the nitrosoamines based on their chemical properties, while the tandem mass spectrometry provides precise mass-to-charge ratio measurements, enabling accurate identification and quantification. Key insights from recent studies indicate that optimizing the chromatographic conditions, such as the choice of stationary phase and mobile phase composition, significantly enhances the resolution and sensitivity of the analysis.…

Seller Inventory # 9786630258103

Title
New method development and validation of sensitive LC-MS/MS method : for Quantification of nitrosoamine impurities in Glimepride active ingredient
Author
Karedla Venkata Veerendra Prasad
Publisher
LAP LAMBERT Academic Publishing
Publication year
2026
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
663025810X
ISBN 13
9786630258103
Item weight
119 grams
Dimensions
220x150x5 mm

AHA-BUCH GmbH

Einbeck, Germany

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AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

Item7 to 10 business days5 to 7 business days
First itemUS$ 39.14US$ 50.32
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