Nonlinear Functional Analysis and its Applications (Hardcover)

Hardcover. As long as a branch of knowledge offers an abundance of problems, it is full of vitality. David Hilbert Over the last 15 years I have given lectures on a variety of problems in nonlinear functional analysis and its applications. In doing this, I have recommended to my students a number of excellent monographs devoted to specialized topics, but there was no complete survey-type exposition of nonlinear functional analysis making available a quick survey to the wide range of readers including mathematicians, natural scientists, and engineers who have only an elementary knowledge of linear functional analysis. I have tried to close this gap with my five-part lecture notes, the first three parts of which have been published in the Teubner-Texte series by Teubner-Verlag, Leipzig, 1976, 1977, and 1978. The present English edition was translated from a completely rewritten manuscript which is significantly longer than the original version in the Teubner-Texte series. The material is organized in the following way: Part I: Fixed Point Theorems. Part II: Monotone Operators. Part III: Variational Methods and Optimization. Parts IV jV: Applications to Mathematical Physics. The exposition is guided by the following considerations: (a) What are the supporting basic ideas and what intrinsic interrelations exist between them? (/3) In what relation do the basic ideas stand to the known propositions of classical analysis and linear functional analysis? ( y) What typical applications are there? Vll Preface viii Special emphasis is placed on motivation. This volume provides a comprehensive survey of the rationale, techniques and contemporary understanding of those drugs which have significant immunomodulatory activity. Major features of the volume include: an overview of current understanding of the biochemistry of lymphocyte activation, an extensive description of the methodology required for study of lymphocytes and their products; coverage of the interaction between lymphocytes and selected hormones; a synopsis of the current understanding of drugs designed to modify lymphocyte function; and an assessment of the prospects for selecting drugs which might modify the immune response. By presenting immunology as a discipline amenable to investigation by pharmacologists, and in view of the current detailed understanding of molecular mechanisms in immunology, immunotherapy is promised increased attention. This volume summarizes the extent to which such expectations have been fulfilled and allows an assessment of the prospects for progress in lymphocyte pharmacology. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.…