Nuclear Receptors : Methods and Experimental Protocols

Mostafa Z. Badr

ISBN 10: 1493991949 / ISBN 13: 9781493991945

Published by Springer New York, Springer New York, 2019

About this Item

Druck auf Anfrage Neuware - Printed after ordering - This volume presents valuable techniques for studying the class of ligand-activated transcription factors known as nuclear receptors. After a brief overview of the history of the field, chapters cover methods to detect the receptors and their mRNAs in various tissues, protocols to characterize nuclear receptor modulators and activities, their signaling and roles in certain pathogenesis, molecular modeling of nuclear receptor-ligand interactions, as well as the utility of informatics in the field of nuclear receptors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Nuclear Receptors: Methods and Experimental Protocols seeks to aid researchers working toward furthering ourunderstanding of these vital receptors and their role in numerous pathological conditions.

Seller Inventory # 9781493991945

Bibliographic Details

• Title: Nuclear Receptors : Methods and Experimental Protocols
• Publisher: Springer New York, Springer New York
• Publication Date: 2019
• Language: English
• ISBN 10: 1493991949
• ISBN 13: 9781493991945
• Binding: Buch
• Condition: Neu
• Dimensions: 260W x 183H x 24D millimeters 260 millimeters width by 183 millimeters height by 24 millimeters depth
• Weight: 816 grams

About this title

Synopsis

This volume presents valuable techniques for studying the class of ligand-activated transcription factors known as nuclear receptors. After a brief overview of the history of the field, chapters cover methods to detect the receptors and their mRNAs in various tissues, protocols to characterize nuclear receptor modulators and activities, their signaling and roles in certain pathogenesis, molecular modeling of nuclear receptor-ligand interactions, as well as the utility of informatics in the field of nuclear receptors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and cutting-edge, Nuclear Receptors: Methods and Experimental Protocols seeks to aid researchers working toward furthering ourunderstanding of these vital receptors and their role in numerous pathological conditions.