Oncogenes - An Introduction To The Concept Of Cancer Genes

Burck, Kathy B.; Liu, Edison T.; Larrick, James W.

ISBN 10: 0387964231 / ISBN 13: 9780387964232

Published by Springer, 1988

About this Item

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Seller Inventory # ABNR-89367

Bibliographic Details

• Title: Oncogenes - An Introduction To The Concept Of Cancer Genes
• Publisher: Springer
• Publication Date: 1988
• Language: English
• ISBN 10: 0387964231
• ISBN 13: 9780387964232
• Binding: Soft cover
• Condition: New

About this title

Synopsis

"Cancer viruses" have played a paradoxical role in the history of cancer research. Discovered in 1911 by Peyton Rous (1) at the Rockefeller Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campaign to focus attention on viruses as etiological agents in cancer, his plat­ form having been the chemical characterization of the tobacco mosaic virus as a pure protein-correction, ribonucleoprotein-in 1935 (2). This doctrine was a centerpiece of the U.S. National Cancer Crusade of 1971: if human cancers were caused by viruses, the central task was to isolate them and prepare vaccines for immunization. At that point, many observers felt that perhaps too much attention was being devoted to cancer viruses. It was problematic whether viruses played an etiological role in more than a handful of human cancers.

Review

'This book contains several outstanding reviews and important perspectives in a field that seems to be changing every year. It is an important contribution that many people would find useful to review and have on their shelves.' Breast Cancer Research and Treatment 19 1991