The Ontogenesis of Cortical Circuitry: The Spatial Distribution of Synapses in Somesthetic Cortex of Newborn Dog

M. E. Molliver

ISBN 10: 3540047972 / ISBN 13: 9783540047971

Published by Springer, Springer Berlin Heidelberg Jan 1970, 1970

About this Item

This item is printed on demand - Print on Demand Titel. Neuware -The ontogenesis of cortical circuitry is the subject of the investigation reported in this paper! Strategie elements of cortical circuitry are synaptic contacts: sites of neuronal interaction. If we first determine the location of early formed synap ses, we may then seek the pre-and postsynaptic elements, that is, the structures which meet and interact at each synaptic junction. The dynamic aspects of cortical development cannot be studied directly: neuronal growth cannot be observed in an intact brain. The pattern of develop ment can be approached only by the analysis of static properties at multiple ages. We have selected the newborn dog as a starting point for these studies. Our observations have been restricted to a small portion of primary somesthetic cor tex. This region was selected because, in mature cortex, its input and physiologie properties are relatively weIl known. It is particularly advantageous to study a primary sensory projection area because its morphologie development can be di rectly related to its functional development. (A related investigation of the onto genesis of electrical activity in somesthetic cortex of the dog will be reported separately). A selective review of the literature is necessary in order to place this work in the context of a few relevant phenomena of cortical development.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 60 pp. Englisch.

Seller Inventory # 9783540047971

Bibliographic Details

• Title: The Ontogenesis of Cortical Circuitry: The Spatial Distribution of Synapses in Somesthetic Cortex of Newborn Dog
• Publisher: Springer, Springer Berlin Heidelberg Jan 1970
• Publication Date: 1970
• Language: English
• ISBN 10: 3540047972
• ISBN 13: 9783540047971
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 244W x 170H x 4D millimeters 244 millimeters width by 170 millimeters height by 4 millimeters depth
• Weight: 123 grams

About this title

Synopsis

The ontogenesis of cortical circuitry is the subject of the investigation reported in this paper!. Strategie elements of cortical circuitry are synaptic contacts: sites of neuronal interaction. If we first determine the location of early formed synap­ ses, we may then seek the pre-and postsynaptic elements, that is, the structures which meet and interact at each synaptic junction. The dynamic aspects of cortical development cannot be studied directly: neuronal growth cannot be observed in an intact brain. The pattern of develop­ ment can be approached only by the analysis of static properties at multiple ages. We have selected the newborn dog as a starting point for these studies. Our observations have been restricted to a small portion of primary somesthetic cor­ tex. This region was selected because, in mature cortex, its input and physiologie properties are relatively weIl known. It is particularly advantageous to study a primary sensory projection area because its morphologie development can be di­ rectly related to its functional development. (A related investigation of the onto­ genesis of electrical activity in somesthetic cortex of the dog will be reported separately). A selective review of the literature is necessary in order to place this work in the context of a few relevant phenomena of cortical development.