Organic Synthesis

Organic synthesis forms the most important integral part of organic chemistry. This requires a knowledge of all carbon-carbon bonding reactions, functional group modifications, mechanisms of reactions, the stereochemistry of the reactions, protection and de-protection during organic synthesis etc.

Synthesis of an organic compound often a natural product, biologically active had been considered as best supporting evidence for their structure and stereochemistry. It is possible to synthesise compounds resembling natural products and to study their biological activity. With the help of the above, structure-activity relationship can be deduced. Along with Bioinformatics the mechanism and the site of reaction of a drug can be evaluated. This can further help the synthetic organic chemist to synthesise more potent drugs for many diseases.

Table of Contents

• Preface
• Introduction
• Synthetic Approaches
• Retrosynthetic Analysis
• Synthesis of Aliphatic Compounds
• Synthesis of Aromatic Compounds
• Synthesis of Alicyclic Systems
• Synthesis of Heterocyclic Compounds
• Some Special Reagents in Organic Synthesis
• Stereochemistry in Organic Synthesis
• Reactive Intermediates in Organic Synthesis
• Some Useful Name Reactions
• Oxidation and Reduction in Organic Synthesis
• Molecular Rearrangements and Pericyclic Reactions in Organic Synthesis
• Protection of Functional Groups in Synthesis
• Electro Organic Synthesis
• Synthetic Approaches Based on Biosynthesis
• Micro Wave in Organic Synthesis
• Ultrasonic Synthesis
• Computer Aided Organic Synthesis
• Organic Synthesis and Green Chemistry
• Asymmetric Synthesis
• Reference
• Index.

C. K. Charles.: Professor and Head, Department of Chemistry SRM Valliammai Engineering College, SRM Nagar, Tamil Nadu