Origin and Evolution of the Vertebrate Immune System

Language: English

Published by Springer, Springer Vieweg Okt 2011, 2011

3642640788 / 9783642640780

Series: Book 188 of 322 - Current Topics in Microbiology and Immunology

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This item is printed on demand - Print on Demand Titel. Neuware -The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked 'are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals ' Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of 'yes', whereas for agnathans and invertebrate phyla it has been 'no' so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 340 pp. Englisch.…

Seller Inventory # 9783642640780

Title
Origin and Evolution of the Vertebrate Immune System
Author
L. Du Pasquier
Publisher
Springer, Springer Vieweg Okt 2011
Publication year
2011
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3642640788
ISBN 13
9783642640780
Item weight
517 grams
Dimensions
235x155x19 mm
Series
Book 188 of 322: Current Topics in Microbiology and Immunology

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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