Overview of Genetic Factors & Environmental Triggers in the Pathogenes

Wang, Cong-Yi Liu, Shi-Guo Yang, Ping Miao, Zhimin

ISBN 10: 1616687487 / ISBN 13: 9781616687489

Published by NOVA SCIENCE PUBLISHERS INC, 2010

About this Item

LIVRE A L?ETAT DE NEUF. EXPEDIE SOUS 3 JOURS OUVRES. NUMERO DE SUIVI COMMUNIQUE AVANT ENVOI, EMBALLAGE RENFORCE. EAN:9781616687489.

Seller Inventory # 9781616687489

Bibliographic Details

• Title: Overview of Genetic Factors & Environmental Triggers in the Pathogenes
• Publisher: NOVA SCIENCE PUBLISHERS INC
• Publication Date: 2010
• Language: English
• ISBN 10: 1616687487
• ISBN 13: 9781616687489
• Binding: Soft cover
• Condition: Used: Like New

About this title

Synopsis

Tourette's syndrome (TS) is an inheritable, childhood-onset neuropsychiatric disorder characterised by the presence of motor and phonic tics. Despite decades of extensive studies, the exact disease aetiology remains poorly understood. It is believed that susceptibility to TS is determined by the interactions of multiple genetic loci with unknown environmental factors. As a result, a great deal of research has been focused on identifying TS susceptibility genes. Thus far, at least 12 susceptibility loci have been suggested by genome-wide screenings, but none of them has been replicated probably due to genetic heterogeneity. Candidate gene approach has also suggested evidence for several genes relevant to neuronal signalling such as dopamine receptor and serotonin receptor. This book discusses the current state of genetic studies in TS susceptibility.