Oxidative Tissue Injury in Experimental Models of Multiple Sclerosis

Language: English

Published by Südwestdeutscher Verlag Für Hochschulschriften, 2015

3838139356 / 9783838139357

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Multiple sclerosis (MS) is a chronic disease of the central nervous system. A number of different animal models of MS contributed to a better understanding of MS pathology. Additionally, experimental models enabled the development of immune-modulatory therapies for MS patients. In recent years, growing evidence for a major role of oxidative injury in demyelination and neurodegeneration in MS has been emerging. Hence, we aimed to characterise the nature and the extent of oxidative damage in different experimental models in comparison to MS. For this purpose, we emphasised the expression of enzymes involved in reactive species production and the accumulation of oxidised phospholipids and iron, which is a potential amplifier of oxidative damage. The different animal models were triggered by diverse inflammatory mechanisms, each representing distinct aspects of MS pathology. The presented study reports a diverging extent of oxidative injury and underlying mechanisms in different models for inflammatory demyelination.…

Seller Inventory # 9783838139357

Title
Oxidative Tissue Injury in Experimental Models of Multiple Sclerosis
Author
Cornelia Schuh
Publisher
Südwestdeutscher Verlag Für Hochschulschriften
Publication year
2015
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3838139356
ISBN 13
9783838139357
Item weight
286 grams
Dimensions
220x150x11 mm

AHA-BUCH GmbH

Einbeck, Germany

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AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

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