Oxidative Tissue Injury in Experimental Models of Multiple Sclerosis

Language: English

Published by Südwestdeutscher Verlag Für Hochschulschriften Feb 2015, 2015

3838139356 / 9783838139357

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This item is printed on demand - Print on Demand Titel. Neuware -Multiple sclerosis (MS) is a chronic disease of the central nervous system. A number of different animal models of MS contributed to a better understanding of MS pathology. Additionally, experimental models enabled the development of immune-modulatory therapies for MS patients. In recent years, growing evidence for a major role of oxidative injury in demyelination and neurodegeneration in MS has been emerging. Hence, we aimed to characterise the nature and the extent of oxidative damage in different experimental models in comparison to MS. For this purpose, we emphasised the expression of enzymes involved in reactive species production and the accumulation of oxidised phospholipids and iron, which is a potential amplifier of oxidative damage. The different animal models were triggered by diverse inflammatory mechanisms, each representing distinct aspects of MS pathology. The presented study reports a diverging extent of oxidative injury and underlying mechanisms in different models for inflammatory demyelination.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 180 pp. Englisch.…

Seller Inventory # 9783838139357

Title
Oxidative Tissue Injury in Experimental Models of Multiple Sclerosis
Author
Cornelia Schuh
Publisher
Südwestdeutscher Verlag Für Hochschulschriften Feb 2015
Publication year
2015
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3838139356
ISBN 13
9783838139357
Item weight
286 grams
Dimensions
220x150x11 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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