Oxygen Variations, 2nd Edition

ISBN 10: 3725875367 / ISBN 13: 9783725875368

Published by MDPI AG, 2026

About this Item

nach der Bestellung gedruckt Neuware - Printed after ordering - Oxygen is a fundamental regulator of cellular metabolism and survival, with effects extending far beyond energy production. This Reprint offers a multidisciplinary overview of how oxygen fluctuations-such as hypoxia, normoxia, and hyperoxia-act as molecular signals influencing redox balance, gene expression, mitochondrial function, and inflammation. It explores cellular and systemic responses to changing oxygen levels in contexts like exercise, altitude, and oxygen therapy. Key mechanisms include the activation of transcription factors (HIFs, NRF2, NF-¿B), ROS/RNS signaling, and mitochondrial adaptations. Emerging topics such as extracellular vesicle release and tissue-specific responses in the brain, heart, and kidneys are also covered. By integrating molecular insights with physiological and clinical relevance, this Reprint provides a framework for understanding oxygen as a dynamic signaling molecule. It is intended for researchers and clinicians interested in redox biology and oxygen-based interventions.

Seller Inventory # 9783725875368

Bibliographic Details

• Title: Oxygen Variations, 2nd Edition
• Publisher: MDPI AG
• Publication Date: 2026
• Language: English
• ISBN 10: 3725875367
• ISBN 13: 9783725875368
• Binding: Buch
• Condition: Neu
• Dimensions: 250W x 175H x 17D millimeters 250 millimeters width by 175 millimeters height by 17 millimeters depth
• Weight: 670 grams

About this title

Synopsis

Oxygen is a fundamental regulator of cellular metabolism and survival, with effects extending far beyond energy production. This Reprint offers a multidisciplinary overview of how oxygen fluctuations-such as hypoxia, normoxia, and hyperoxia-act as molecular signals influencing redox balance, gene expression, mitochondrial function, and inflammation. It explores cellular and systemic responses to changing oxygen levels in contexts like exercise, altitude, and oxygen therapy. Key mechanisms include the activation of transcription factors (HIFs, NRF2, NF-κB), ROS/RNS signaling, and mitochondrial adaptations. Emerging topics such as extracellular vesicle release and tissue-specific responses in the brain, heart, and kidneys are also covered. By integrating molecular insights with physiological and clinical relevance, this Reprint provides a framework for understanding oxygen as a dynamic signaling molecule. It is intended for researchers and clinicians interested in redox biology and oxygen-based interventions.