PAKs, RAC/CDC42 (p21)-activated Kinases: Towards the Cure of Cancer and Other PAK-dependent Diseases

This book consists of 9 chapters which deal with different aspects of this kinase. These chapters are written by more than two dozen world-leading PAK experts. Each of these will provide updated biomedical information as well as future insight to a wide range of readers who are interested in this unique kinase and both its pathological and physiological roles as well as its functional evolution from its ancestral origins.

• This publication will be the very first book ever published solely focused on PAK family kinases.
• Each chapter deals with the latest progress in PAK research written by a leading PAK expert with his or her own ideas and insight.  
• Each chapter of this book has been written in such a way that clinical doctors who seek the effective cure of these formidable diseases, in addition to research scientists and biomedical students will value this book.
• This book describes in detail a number of PAK blockers which would be potentially useful for the therapy of these PAK-dependent diseases, and some of them are indeed available on the market inexpensively, without any side effect.

"Here neurologists and other biomedical researchers explain in some detail how PAKs ― particularly the oncogenic kinases PAK1 and PAK4 and their blockers ― may control various aspects of life and health, and how mammalian PAKs have functionally evolved from their ancestral origins in unicellular organisms such as yeast and amoebas through a series of mutations over millions of years."--Reference and Research Book News, August 2013