THE PARADOX OF LEAD TOXICITY : DNA DAMAGE STUDIES ON LEAD EXPOSED INDIVIDUALS USING MOLECULAR AND COMPUTATIONAL APPROACHES

Language: English

Published by LAP LAMBERT Academic Publishing, 2010

3838304527 / 9783838304526

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Lead is widely used in hundreds of products but it is non-biodegradable, hence it is simultaneously a versatile product and at the same time a subtle and persistent poison. This is the paradox of lead toxicity. Exposure to lead is a threat to the health and to physical development of young children and adults. The characteristic features of lead toxicity, including anemia, colic, neuropathy, nephropathy, sterility, and coma, were noted both by Hippocrates and Nikander in ancient times. We found that lower concentration of lead could induce significant DNA damage and strand breaks in the chromosomes. Biomarkers of Molecular toxicity studies showed DNA strand breaks, micro nuclei, apoptosis and necrosis. Lead is a genotoxicant and certain factors like, duration of exposure and habitats and other demographic factors of the individuals enhance the toxicity. It was found that hemoglobin levels were comparatively low in volunteers with higher blood lead levels, but there was a definite role of other factors like nutritional status, calcium and Iron intake and genotypes of certain genes of the individuals.…

Seller Inventory # 9783838304526

Title
THE PARADOX OF LEAD TOXICITY : DNA DAMAGE STUDIES ON LEAD EXPOSED INDIVIDUALS USING MOLECULAR AND COMPUTATIONAL APPROACHES
Author
Kaiser Jamil
Publisher
LAP LAMBERT Academic Publishing
Publication year
2010
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3838304527
ISBN 13
9783838304526
Item weight
328 grams
Dimensions
220x150x14 mm

AHA-BUCH GmbH

Einbeck, Germany

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