PBC The Definitive Guide for Patients with Primary Biliary Cholangitis: 2026 Edition

This is the 2026 Edition of this highly acclaimed book for people with the liver disease primary biliary cholangitis (PBC), fully updated and expanded to take account of the substantial progress and changes in the field.

THIS BOOK WILL GIVE YOU ALL THE INFORMATION YOU NEED TO DECIDE WHICH OF THE NEW PBC TREATMENTS IS THE RIGHT ONE FOR YOU, AND WHAT YOU SHOULD DO IF YOU NEED TO CHANGE TREATMENT

New for the 2026 edition

• Explanation of the changes in the availability of PBC drugs that will impact on you.
• Detailed information of the new drugs now available to treat PBC, including Seladelpar and Elafibranor and combination therapy regimes
• Guidance on which treatment might be the right one for you; a really important issue when there are now multiple treatments that are available, and how to go about making a treatment change
• Information on the new targets for treatment, including normalisation of blood tests as a treatment goal
• New thinking on how we follow up PBC in practice, including the role of Fibroscan
• Guidance on the questions that you should be asking your doctor to make sure you get the best possible treatment for your PBC, especially around choice of treatment
• Expanded “frequently asked questions” section answering more of the questions that you have asked since the last edition
• All the latest thinking on why PBC patients get itch, fatigue, brain fog and other symptoms and what we can do about them (including information on the new itch treatments)
• Downloadable record sheets for your blood test numbers and symptoms to guide your clinic consultations

This is the fully updated 4th edition of the definitive guide to help patients with PBC live with the condition. Treatments for PBC have advanced rapidly in recent years and we are in a better position than ever to completely control it. With the information in this book you can make sure you are getting the best possible treatment, and find out what you can do to help yourself. Written by one of the world's leading experts on PBC, this book explains all aspects of the condition, from why people get it, to how it is diagnosed in the clinic, how it is treated and how you can beat the symptoms. It can be read as a thorough explanation; a textbook for patients. Alternatively, with "two-minute versions" for each of the chapters, you can get all the key facts quickly. The book also has a dictionary of PBC which will help you understand the technical terms and medical jargon that you may encounter. The book is also ideal for the relatives and partners of PBC patients to help them better understand their loved one's medical problems. It will also be really useful for students, doctors, nurses and other professionals who are encountering PBC for the first time and want to find out more.

What people said about the first 3 editions
" An excellent book.....thank you for writing this" S
“If you have PBC this is a must have book” C
“This book is a bible for PBC” SS
" This book is an absolute godsend......this amazing book is a must have for all PBC patients and their families" JP
"An essential purchase" C
"Professor Jones is amazing, thank you so much for writing this invaluable book" LE
"Every piece of information you need to know and more is contained within this bible" PL
“Professor Jones is the rockstar of PBC” MC