PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF PHASEOLUS LUNATUS IN RATS

Language: English

Published by LAP LAMBERT Academic Publishing Apr 2023, 2023

6206156281 / 9786206156284

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -The study was taken up to evaluate the pharmacological and toxicological property of Phaseolus lunatus (P. lunatus) plant. Phytochemical analysis revealed the presence of carbohydrates, proteins, saponins, alkaloids, flavonoids and phenolic compounds. The study was conducted to evaluate the in vivo anti-inflammatory property of the plant extract using carrageenan induced paw oedema and the extract at the doses of 400 and 600 mg/kg is having significant anti-inflammatory activity. In vivo analgesic activity was conducted by using acetic acid induced writhings as peripheral pain model and the extract at the doses 400 and 600 mg/kg showed significant analgesic activity. Acute oral and repeated dose 28 day oral toxicity studies of methanol extract was carried out in Wistar albino rats as per the OECD guidelines 423 and 407 respectively. In sub-acute oral toxicity dose levels of 200, 400 and 600 mg/kg were administered daily for 28 days and compared with the control rats. In both toxicity studies, no toxicity signs and mortality were observed. The MTD value was found to be more than 5 g/kg. No significant (p<0.05) changes in hematological parameters and biochemical parameters. 116 pp. Englisch.

Seller Inventory # 9786206156284

Title
PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF PHASEOLUS LUNATUS IN RATS
Author
Punith K. G.
Publisher
LAP LAMBERT Academic Publishing Apr 2023
Publication year
2023
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6206156281
ISBN 13
9786206156284
Item weight
191 grams
Dimensions
220x150x7 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany