PPAR gene polymorphisms and Infertility | Study of the relation between PPAR gene polymorphisms and PPAR protein level in human granoloza cells with ART success | Mohammad Nouri (u. a.) | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9783848423521 | Verantwortliche Person f�r die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabr�ck, mail[at]preigu[dot]de | Anbieter: preigu.

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Bibliographic Details

Title

PPAR gene polymorphisms and Infertility | Study of the relation between PPAR gene polymorphisms and PPAR protein level in human granoloza cells with ART success

Publisher

LAP Lambert Academic Publishing

Publication Date

2012

Language

English

ISBN 10

3848423529

ISBN 13

9783848423521

Binding

Taschenbuch

Condition

Neu

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About this title

Synopsis

Infertility is one of the prevalent disorders among communities, especially in women of childbearing age. Today, ART (assisted reproductive technology) such as IVF(in-vitro fertilization) and ICSI(Intra Cytoplasmic Sperm Injection) are used for treatment of infertile couples. Genetic factors have a crucial role in fertility and fetal development and the success of ART can be highly effected by these factors. In the present study, the relationship between HIS447His and Pro12Ala polymorphisms of PPARγ gene and also the PPARγ protein level with the number of oocyte and fertility rate in women candidate for IVF has been investigated. According of the results of this study two common polymorphisms in PPARγ gene may have an important role in-vitro fertilization and possibly rate. In addition no significant relation was found between PPARγ protein concentration in granoloza cell and the ART success rate.

About the Author

I am an associate-professor of Clinical Biochemistry in Faculty of Medicine, Tabriz University of Medical Sciences. I have certificate A.R.T. lab. technique, ICSI and IVF from Wife Hospital, Kiel University, Kiel, Germany and also Health Policy, Planning, and Economics from Nuffield Institute, Leeds, UK.

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