PPARs as Key Mediators of Metabolic and Inflammatory Regulation

ISBN 10: 3036541926 / ISBN 13: 9783036541921

Published by MDPI AG, 2022

About this Item

PPARs as Key Mediators of Metabolic and Inflammatory Regulation | Buch | Gebunden | Englisch | 2022 | MDPI AG | EAN 9783036541921 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand.

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Bibliographic Details

• Title: PPARs as Key Mediators of Metabolic and Inflammatory Regulation
• Publisher: MDPI AG
• Publication Date: 2022
• Language: English
• ISBN 10: 3036541926
• ISBN 13: 9783036541921
• Binding: Buch
• Condition: Neu
• Dimensions: 250W x 175H x 34D millimeters 250 millimeters width by 175 millimeters height by 34 millimeters depth
• Weight: 1339 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

Mounting evidence suggests a bidirectional relationship between metabolism and inflammation. Molecular crosstalk between these processes occurs at different levels with the participation of nuclear receptors, including peroxisome proliferator-activated receptors (PPARs). There are three PPAR isotypes, α, β/δ, and γ, which modulate metabolic and inflammatory pathways, making them key for the control of cellular, organ, and systemic processes. PPAR activity is governed by fatty acids and fatty acid derivatives, and by drugs used in clinics (glitazones and fibrates). The study of PPAR action, also modulated by post-translational modifications, has enabled extraordinary advances in the understanding of the multifaceted roles of these receptors in metabolism, energy homeostasis, and inflammation both in health and disease. This Special Issue of IJMS includes a broad range of basic and translational article, both original research and reviews, focused on the latest developments in the regulation of metabolic and/or inflammatory processes by PPARs in all organs and the microbiomes of different vertebrate species.